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State Reconstruction in Spatially Distributed BioProcess Systems using Reduced Order Models: Application to the Gluconic Acid Production.

García, Míriam R. and Vilas, Carlos and Banga, Julio R. and Lyubenova, Velislava N. and Ignatova, Maya N. and Alonso, Antonio A. (2005) State Reconstruction in Spatially Distributed BioProcess Systems using Reduced Order Models: Application to the Gluconic Acid Production. Decision and Control, 2005 and 2005 European Control Conference. CDC-ECC '05. 44th IEEE Conference on : ISBN 0-7803-9567-0 . pp. 6256-6261.

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Abstract

In this work, the dissipative nature of spatially distributed bioprocess systems is exploited to develop efficient state observers based on a low dimensional dynamic representation of the original set of partial differential equations. The approach we suggest combines standard observer design techniques for bioreactors with efficient model reduction methodologies based on projection of the original concentration fields on low dimensional subspaces capturing the slow dynamics of the process. Aspects related with the location of sensors and their influence on the ability to reconstruct concentration fields will also be considered. Finally, the different aspects of the methodology, as well as the efficiency of the resulting observers will be illustrated on a case study of industrial interest, namely a tubular bioreactor producing gluconic acid by Aspergillus Niger.

Item Type: Article
Additional Information: This paper includes results of the joint research project that is supported by the bilateral agreements between Bulgarian academy of sciences and Process Engineering Group IIMCSIC. The authors acknowledge financial support received from the Spanish Government (MCyT Projects PPQ2001- 3643) and Xunta de Galicia (PGIDIT02-PXIC40209PN).
Keywords: State Reconstruction; Spatially Distributed BioProcess Systems; Reduced Order Models; Gluconic Acid Production;
Subjects: Science & Engineering > Hamilton Institute
Item ID: 1908
Identification Number: DOI: 10.1109/CDC.2005.1583164
Depositing User: Hamilton Editor
Date Deposited: 23 Nov 2010 16:18
Journal or Publication Title: Decision and Control, 2005 and 2005 European Control Conference. CDC-ECC '05. 44th IEEE Conference on : ISBN 0-7803-9567-0
Publisher: IEEE
Refereed: Yes
URI:

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