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Examination of the bovine leukocyte environment using immunogenetic biomarkers to assess immunocompetence following exposure to weaning stress

O'Loughlin, Aran and McGee, Mark and Waters, Sinead M. and Doyle, Sean and Earley, Bernadette (2011) Examination of the bovine leukocyte environment using immunogenetic biomarkers to assess immunocompetence following exposure to weaning stress. Veterinary Research, 7 (45). ISSN 0928-4249

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Abstract

The molecular mechanisms by which stress induces the development of pathologies remains unclear, although it is recognised that one of the major factors affecting health as a consequence of stress is the involvement of the neuroendocrine system. In cattle, a number of necessary husbandry practices have been shown to activate the stress response, yet very little is known about the impact these have at the molecular level. The objectives of the study were to characterise, in male and female beef calves, the immune response to weaning stress in bovine leukocytes at the physiological and molecular levels and to assess the difference between calves weaned in the presence of the dam and those weaned and penned away from the dam.

Item Type: Article
Keywords: bovine leukocyte; immunogenetic biomarkers; immunocompetence; weaning stress;
Subjects: Science & Engineering > Biology
Item ID: 3035
Identification Number: 10.1186/1746-6148-7-45
Depositing User: Dr. Sean Doyle
Date Deposited: 27 Jan 2012 12:01
Journal or Publication Title: Veterinary Research
Publisher: BioMed Central
Refereed: Yes
URI:

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