Valente, Sabrina and Ringwood, John and Mangourova, Violeta and Lowry, John
Investigation of events in the EEG signal correlated
with changes in both oxygen and glucose in the brain.
In: ISSC 2012, 28-29 June, 2012, NUI Maynooth.
Since the brain has no constant energy reserves, a continuous supply of energy
substrates is central to all processes that maintain the functionality of the neuronal cells.
EEG has been found to be tightly related to variations in the concentration of the energy
substrates such as oxygen and glucose. Prediction of neural activation is particularly useful
as it could contribute significantly in the prevention, stabilization, or treatment of diseases
such as Alzheimer's disease, migraine headache, and ischemic stroke, in which signaling
between neurons and brain vessels is threatened because of dysfunctions that affect the
neuronal, astroglial, and/or vascular components of the neurovascular unit. This work deals
with investigation of events in the EEG signal correlated with changes in both oxygen and
glucose signals in the brain. The topic is to implement a model that through measures of
oxygen and glucose in the brain of rats allow to achieve a good estimation of the neural
signals, which reflecting the simultaneous metabolic changes, during spontaneous oscillation
and electrical stimulation.
Conference or Workshop Item
||neuronal activation; brain metabolism; energy substrates; system identification;
||Science & Engineering > Electronic Engineering
Professor John Ringwood
||17 Sep 2012 11:04
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