Article

Downes, Shane G., Owens, Rebecca A., Walshe, Kieran, Fitzpatrick, David A., Dorey, Amber, Jones, Gary W. and Doyle, Sean (2023) Gliotoxin-mediated bacterial growth inhibition is caused by specific metal ion depletion. Scientific Reports, 13 (1). ISSN 2045-2322

Traynor, Aimee M., Sarikaya-Bayram, Özlem, Bayram, Ozgur, Antonio Calera, José and Doyle, Sean (2023) Proteomic dissection of the role of GliZ in gliotoxin biosynthesis in Aspergillus fumigatus. Fungal Genetics and Biology, 166. p. 103795. ISSN 1087-1845

Smith, Helen, Doyle, Sean and Murphy, Richard (2023) Target directed identification of natural bioactive compounds from filamentous fungi. Food Chemistry, 405 (Part A). pp. 1-8. ISSN 0308-8146

Borges, Bruno Montanari, Ramos, Rafael Berton Correia, Preite, Nycolas Willian, Kaminski, Valéria de Lima, Alves de Castro, Patrícia, Camacho, Maurício, Maximo, Marina Ferreira, Fill, Taicia Pacheco, Calich, Vera Lúcia Garcia, Traynor, Aimee M., Sarikaya-Bayram, Özlem, Doyle, Sean, Bayram, Ozgur, de Campos, Claudia Barbosa Ladeira, Zelanis, André, Goldman, Gustavo H. and Loures, Flávio Vieira (2023) Transcriptional profiling of a fungal granuloma reveals a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host immune response. Frontiers in Cellular and Infection Microbiology, 13. pp. 1-27. ISSN 2235-2988

Abdel-Moneim, Ahmed S., Berre, Marie Le, Paulovčáková, Terézia, Verissimo, Carolina De Marco, Doyle, Sean, Dalton, John P., Masterson, Claire, Martínez, Eduardo Ribes, Walsh, Laura, Gormley, Conor, Laffey, John G., McNicholas, Bairbre, Simpkin, Andrew J. and Kilcoyne, Michelle (2023) A new multiplex SARS-CoV-2 antigen microarray showed correlation of IgG, IgA, and IgM antibodies from patients with COVID-19 disease severity and maintenance of relative IgA and IgM antigen binding over time. PLOS ONE, 18 (3). pp. 1-31. ISSN 1932-6203

Rawlings, Anna, O'Connor, Eoin, Moody, Suzy C., Dudley, Ed, Boddy, Lynne, Fowler, Mike S., Fitzpatrick, David A., Doyle, Sean and Eastwood, Dan C. (2022) Metabolic responses of two pioneer wood decay fungi to diurnally cycling temperature. Journal of Ecology, 110 (1). pp. 68-79. ISSN 0022-0477

De Marco Verissimo, Carolina, López Corrales, Jesús, Dorey, Amber L., Cwiklinski, Krystyna, Lalor, Richard, Calvani, Nichola Eliza Davies, Jewhurst, Heather L., Flaus, Andrew, Doyle, Sean and Dalton, John P. (2022) Production of a functionally active recombinant SARS-CoV-2 (COVID-19) 3C-like protease and a soluble inactive 3C-like protease-RBD chimeric in a prokaryotic expression system. Epidemiology and Infection, 150. ISSN 0950-2688

Doyle, Sean, Cuskelly, Daragh D., Conlon, Niall, Fitzpatrick, David A., Gilmartin, Ciara B., Dix, Sophia H. and Jones, Gary W. (2022) A Single Aspergillus fumigatus Gene Enables Ergothioneine Biosynthesis and Secretion by Saccharomyces cerevisiae. International Journal of Molecular Sciences, 23 (18). p. 10832. ISSN 1422-0067

Traynor, Aimee M., Owens, Rebecca A., Coughlin, Claudia M., Holton, Maeve C., Jones, Gary W., Calera, José A. and Doyle, Sean (2021) At the metal–metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin. Microbiology, 167 (11). ISSN 1350-0872

Traynor, Aimee M., Owens, Rebecca A., Coughlin, Claudia M., Holton, Maeve C., Jones, Gary W., Calera, José A. and Doyle, Sean (2021) At the metal–metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin. Microbiology, 167 (11). ISSN 1350-0872

Moloney, Nicola M., Larkin, Annemarie, Xu, Linan, Fitzpatrick, David A., Crean, Holly L., Walshe, Kieran, Haas, Hubertus, Decristoforo, Clemens and Doyle, Sean (2021) Generation and characterisation of a semi-synthetic siderophore-immunogen conjugate and a derivative recombinant triacetylfusarinine C–specific monoclonal antibody with fungal diagnostic application. Analytical Biochemistry, 632. p. 114384. ISSN 0003-2697

De Marco Verissimo, Carolina, O'Brien, Carol, López Corrales, Jesús, Dorey, Amber, Cwiklinski, Krystyna, Lalor, Richard, Doyle, Jack M., Field, Stephen, Masterson, Claire, Ribes Martinez, Eduardo, Hughes, Gerry, Bergin, Colm, Walshe, Kieran, McNicholas, Bairbre, Laffey, John G., Dalton, John P., Kerr, Colm and Doyle, Sean (2021) Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests. Epidemiology and Infection, 149 (e140). pp. 1-11. ISSN 0950-2688

Xu, Linan, Zhang, Hong, Cuskelly, Daragh D., Doyle, Sean, Perrett, Sarah and Jones, Gary W. (2021) Mutational analysis of the Hsp70 substrate‐binding domain: Correlating molecular‐level changes with in vivo function. Molecular Microbiology, 115 (6). pp. 1262-1276. ISSN 0950-382X

O'Connor, Eoin, Doyle, Sean, Amini, Aniça, Grogan, Helen and Fitzpatrick, David A. (2021) Transmission of mushroom virus X and the impact of virus infection on the transcriptomes and proteomes of different strains of Agaricus bisporus. Fungal Biology, 125 (9). pp. 704-717. ISSN 1878-6146

Ries, Laure Nocolas Annick, Pardeshi, Lakhansing, Dong, Zhiqiang, Tan, Kaeling, Steenwyk, Jacob L, Colabardini, Ana Christina, Ferreira Filho, Jaire A., de Castro, Patricia A., Silva, Lilian Pereira, Preite, Nycolas W, Almeida, Fausto, de Assis, Leandro J, dos Santos, Renato A C, Bowyer, Paul, Bromley, Michael, Owens, Rebecca A., Doyle, Sean, Demasi, Marilene, Hernandez, Diego C R, Netto, Luis Eduardo S, Pupo, Monica T, Rokas, Antonis, Loures, Flavio V, Wong, Koon H and Goldman, Gustavo H (2020) The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence. PLOS Pathogens, 16 (7). e1008645. ISSN 1553-7366

O’Connor, Eoin, Owens, Rebecca A., Doyle, Sean, Amini, Aniça, Grogan, Helen and Fitzpatrick, David A. (2020) Proteomic investigation of interhyphal interactions between strains of Agaricus bisporus. Fungal Biology, 124 (6). pp. 579-591. ISSN 18786146

Scott, Jennifer, Sueiro-Olivares, Monica, Thornton, Benjamin P, Owens, Rebecca A., Muhamadali, Howbeer, Fortune-Grant, Rachael, Thomson, Darren, Thomas, Riba, Hollywood, Katherine, Doyle, Sean, Goodacre, Royston, Tabernero, Lydia, Bignell, Elaine and Amich, Jorge (2020) Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence. mBio, 11 (5). e01985-20. ISSN 2150-7511

Waldron, Rose, McGowan, Jamie, Gordon, Natasha, Mitchell, E Bruce, Fitzpatrick, David A. and Doyle, Sean (2019) Characterisation of three novel ß-1,3 glucanases from the medically important house dust mite Dermatophagoides pteronyssinus (airmid). Insect Biochemistry and Molecular Biology, 115 (103242). ISSN 0965-1748

Sarikaya-Bayram, Ozlem, Dettmann, Anne, Karahoda, Betim, Moloney, Nicola M., Ormsby, Tereza, McGowan, Jamie, Cea-Sánchez, Sara, Miralles-Duran, Alejandro, Brancini, Guilherme T P, Luque, Eva, Fitzpatrick, David A., Canovas, David, Corrochano, Luis M, Doyle, Sean, Selker, Eric U, Seiler, Stephen and Bayram, Ozgur (2019) Control of development, secondary metabolism and light-dependent carotenoid biosynthesis by the velvet complex of Neurospora crassa. Genetics, 212 (3). pp. 691-710. ISSN 0016-6731

Traynor, Aimee M, Sheridan, Kevin J, Jones, Gary W, Calera, José A and Doyle, Sean (2019) Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, particularly Aspergillus spp.: Molecular and Therapeutic Implications. Frontiers in Microbiology, 10 (2859). ISSN 1664-302X

Xu, Linan, Nitika, Hasin, Naushaba, Cuskelly, Daragh, Wolfgeher, Donald, Doyle, Sean, Moynagh, Paul N., Perrett, Sarah, Jones, Gary W. and Truman, Andrew W. (2019) Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress. Scientific Reports, 9 (16260). ISSN 2045-2322

Reece, Emma, Doyle, Sean, Greally, Peter, Renwick, Julie and McClean, Siobhan (2018) Aspergillus fumigatus Inhibits Pseudomonas aeruginosa in Co-culture: Implications of a Mutually Antagonistic Relationship on Virulence and Inflammation in the CF Airway. Frontiers in Microbiology, 9 (1205). ISSN 1664-302X

Doyle, Sean, Jones, Gary W. and Dolan, Stephen K. (2018) Dysregulated gliotoxin biosynthesis attenuates the production of unrelated biosynthetic gene cluster-encoded metabolites in Aspergillus fumigatus. Fungal Biology, 122. pp. 214-221. ISSN 1878-6146

Saleh, Aliabbas A., Jones, Gary W., Tinley, Frances C., Delaney, Stephen F., Alabaddi, Sahar H., Fenlon, Keith, Doyle, Sean and Owens, Rebecca A. (2018) Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in Aspergillus fumigatus: a new direction in natural product functionality. Metallomics, 10. pp. 854-866. ISSN 1756-591X

Cullen, Louise, O'Connor, Andrew, McCormack, Sarah, Owens, Rebecca A., Holt, Giles S., Collins, Cassandra, Callaghan, Maire, Doyle, Sean, Smith, Darren, Schaffer, Kirsten, Fitzpatrick, David A. and McClean, Siobhan (2018) The involvement of the low-oxygen-activated locus of Burkholderia cenocepacia in adaptation during cystic fibrosis infection. Scientific Reports, 8 (1). p. 13386. ISSN 2045-2322

Waldron, Rose, McGowan, Jamie, Gordon, Natasha, McCarthy, Charley G.P., Mitchell, E. Bruce, Doyle, Sean and Fitzpatrick, David A. (2017) Draft Genome Sequence of Dermatophagoides pteronyssinus, the European House Dust Mite. Genome Announcments, 5 (2). e00789-17. ISSN 2169-8287

Mulvihill, Eoin, Moloney, Nicola M., Owens, Rebecca A., Dolan, Stephen K., Russell, Lauren and Doyle, Sean (2017) Functional Investigation of Iron-Responsive Microsomal Proteins, including MirC, in Aspergillus fumigatus. Frontiers in Microbiology, 8 (418). ISSN 1664-302X

Sipos, György, Prasanna, Arun N., Walter, Mathias C., Krizsán, Krisztina, Kiss, Brigitta, Hess, Jaqueline, Varga, Torda, Slot, Jason, Riley, Robert, Bóka, Bettina, Rigling, Daniel, Barry, Kerrie, Lee, Juna, Mihaltcheva, Sirma, LaButti, Kurt, Lipzen, Anna, Waldron, Rose, Moloney, Nicola M., Sperisen, Christoph, Kredics, László, Vágvölgyi, Csaba, Patrignani, Andrea, Fitzpatrick, David A., Nagy, István, Doyle, Sean, Anderson, James B., Grigoriev, Igor V., Münsterkötter, Martin and Nagy, László (2017) Genome expansion and lineage-specific genetic innovations in the forest pathogenic fungi Armillaria. Nature Ecology & Evolution, 1. pp. 1931-1941. ISSN 2397-334X

Delgado, Josué, Owens, Rebecca A., Doyle, Sean, Núñez, Felix and Asensio, Miguel A. (2017) Quantitative proteomics reveals new insights into calcium-mediated resistance mechanisms in Aspergillus flavus against the antifungal protein PgAFP in cheese. Food Microbiology, 66. pp. 1-10. ISSN 1095-9998

Dolan, Stephen K., Bock, Tobias, Hering, Vanessa, Owens, Rebecca A., Jones, Gary W., Blankenfeldt, Wulf and Doyle, Sean (2017) Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus. Open Biology, 7 (2). ISSN 2046-2441

Alves de Castro, Patricia, dos Reis, Thaila Fernanda, Dolan, Stephen K., Manfiolli, Adriana Oliveira, Brown, Neil Andrew, Jones, Gary W., Doyle, Sean, Riaño‐Pachón, Diego M., Squina, Fabio M., Caldana, Camila, Singh, Ashutosh, Del Poeta, Maurizio, Hagiwara, Daisuke, Silva-Rocha, Rafael and Goldman, Gustavo H. (2016) The Aspergillus fumigatus SchASCH9 kinase modulates SakAHOG1 MAP kinase activity and it is essential for virulence. Molecular Microbiology, 102 (4). pp. 642-671. ISSN 1365-2958

Sheridan, Kevin J., Lechner, Beatrix Elizabeth, O'Keeffe, Grainne, Keller, Markus A., Werner, Ernst R., Lindner, Herbert, Jones, Gary W., Haas, Hubertus and Doyle, Sean (2016) Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus. Scientific Reports, 6 (35306). ISSN 2045-2322

Amich, Jorge, Dümig, Michaela, O'Keeffe, Grainne, Binder, Jasmin, Doyle, Sean, Beilhack, Andreas and Krappmann, Sven (2016) Exploration of Sulfur Assimilation of Aspergillus fumigatus Reveals Biosynthesis of Sulfur-Containing Amino Acids as a Virulence Determinant. Infection and Immunity, 84 (4). pp. 917-929. ISSN 0019-9567

Delgado, Josué, Owens, Rebecca A., Doyle, Sean, Asensio, Miguel A. and Núñez, Felix (2016) Increased chitin biosynthesis contributes to the resistance of Penicillium polonicum against the antifungal protein PgAFP. Applied Microbiology and Biotechnology, 100 (1). pp. 371-383. ISSN 1432-0614

McClean, Siobhan, Healy, Mark E., Collins, Cassandra, Carberry, Stephen, O'Shaughnessy, Like, Dennehy, Ruth, Adams, Aine, Kennelly, Helen, Corbett, Jennifer, Carty, Fiona, Cahill, Laura A., Callaghan, Maire, English, Karen, Mahon, Bernard P., Doyle, Sean and Shinoy, Minu (2016) Linocin and OmpW Are Involved in Attachment of the Cystic Fibrosis-Associated Pathogen Burkholderia cepacia Complex to Lung Epithelial Cells and Protect Mice against Infection. Infection and Immunity, 84 (5). pp. 1424-1437. ISSN 0019-9567

Delgado, Josué, Owens, Rebecca A., Doyle, Sean, Asensio, Miguel A. and Núñez, Felix (2016) Manuscript title: antifungal proteins from moulds: analytical tools and potential application to dry-ripened foods. Applied Microbiology and Biotechnology, 100 (16). pp. 6991-7000.

Manzanares-Miralles, Lara, Bayram, Ozgur, Sarikaya-Bayram, Ozlem, Smith, Elizabeth B., Dolan, Stephen K., Jones, Gary W. and Doyle, Sean (2016) Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger. Journal of Proteomics, 131. pp. 149-162. ISSN 1874-3919

Smith, Elizabeth B., Dolan, Stephen K., Fitzpatrick, David A., Doyle, Sean and Jones, Gary W. (2016) Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity. Microbial Cell, 3 (3). pp. 120-125. ISSN 2311-2638

Moloney, Nicola M., Owens, Rebecca A., Meleady, Paula, Henry, Michael, Dolan, Stephen K., Mulvihill, Eoin, Clynes, Martin and Doyle, Sean (2016) The iron-responsive microsomal proteome of Aspergillus fumigatus. Journal of Proteomics, 136. pp. 99-111. ISSN 1874-3919

Fagan, Sheena, Owens, Rebecca A., Ward, Patrick, Connolly, Cathal, Doyle, Sean and Murphy, Richard (2015) Biochemical Comparison of Commercial Selenium Yeast Preparations. Biological Trace Element Research, 166. pp. 245-259. ISSN 0163-4984

Sheridan, Kevin J., Dolan, Stephen K. and Doyle, Sean (2015) Endogenous cross-talk of fungal metabolites. Frontiers in Microbiololgy, 5 (732). pp. 1-11. ISSN 1664-302X

Smith, Helen A., Doyle, Sean and Murphy, Richard (2015) Filamentous fungi as a source of natural antioxidants. Food Chemistry, 185. pp. 389-397. ISSN 0308-8146

Owens, Rebecca A., O'Keeffe, Grainne, Smith, Elizabeth B., Dolan, Stephen K., Hammel, Stephen, Sheridan, Kevin J., Fitzpatrick, David A., Keane, Thomas M. and Doyle, Sean (2015) Interplay between Gliotoxin Resistance, Secretion, and the Methyl/ Methionine Cycle in Aspergillus fumigatus. Eukaryotic Cell, 14 (9). pp. 941-957. ISSN 1535-9786

Medema, M.H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J.B., Blin, K., de Bruijn, I., Chooi, Y.H., Claesen, J., Coates, R.C., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D.J., Fewer, D.P., Garg, N., Geiger, C., Gomez-Escribano, J.P., Greule, A., Hadjithomas, M., Haines, A.S., Helfrich, E.J., Hillwig, M.L., Ishida, K., Jones, A.C., Jones, C.S., Jungmann, K., Kegler, C., Kim, H.U., Kötter, P., Krug, D., Masschelein, J., Melnik, A.V., Mantovani, S.M., Monroe, E.A., Moore, M., Moss, N., Nützmann, H.W., Pan, G., Pati, A., Petras, D., Reen, F.J., Rosconi, F., Rui, Z., Tian, Z., Tobias, N.J., Tsunematsu, Y., Wiemann, P., Wyckoff, E., Yan, X., Yim, G., Yu, F., Xie, Y., Aigle, B., Apel, A.K., Balibar, C.J., Balskus, E.P., Barona-Gómez, F., Bechthold, A., Bode, H.B., Borriss, R., Brady, S.F., Brakhage, Axel A., Caffrey, P., Cheng, Yo, Clardy, J., Cox, R.J., De Mot, R., Donadio, S., Donia, M.S., van der Donk, W.A., Dorrestein, P.C., Doyle, Sean, Driessen, A.J., Ehling-Schulz, M., Entian, K.D., Fischbach, M.A., Gerwick, L., Gerwick, W.H., Gross, H., Gust, B., Hertweck, C., Höfte, M., Jensen, S.E., Ju, J., Katz, L., Kaysser, L., Klassen, J.L., Keller, N.P., Kormanec, J., Kuipers, O.P., Kuzuyama, T., Kyrpides, N.C., Kwon, H.J., Lautru, S., Lavigne, R., Lee, C.Y., Linquan, B., Liu, X., Liu, W., Luzhetskyy, A., Mahmud, T., Mast, Y., Méndez, C., Metsä-Ketelä, M., Micklefield, J., Mitchell, D.A., Moore, B.S., Moreira, L.M., Muller, R., Neilan, B.A., Nett, M., Nielsen, J., O'Gara, F., Oikawa, H., Osbourn, A., Osburne, M.S., Ostash, B., Payne, S.M., Pernodet, J.L., Petricek, M., Piel, J., Ploux, O., Raaijmakers, J.M., Salas, J.A., Schmitt, E.K., Scott, B., Seipke, R.F., Shen, B., Sherman, D.H., Sivonen, K., Smanski, M.J., Sosio, M., Stegmann, E., Süssmuth, R.D., Tahlan, K., Thomas, C.M., Tang, Y., Truman, A.W., Viaud, M., Walton, J.D., Walsh, C.T., Weber, T., van Wezel, G.P., Wilkinson, B., Willey, J.M., Wohlleben, W., Wright, G.D., Ziemert, N., Zhang, C., Zotchev, S.B., Breitling, R., Takano, E. and Glöckner, F.O. (2015) Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology, 11 (9). pp. 625-631. ISSN 1552-4469

Dolan, Stephen K., O'Keefe, Grainne, Jones, Gary W. and Doyle, Sean (2015) Resistance is not futile: gliotoxin biosynthesis, functionality and utility. Trends in Microbiology, 23 (7). pp. 419-428. ISSN 0966-842X

Winkelstroter, Lizziane K., Dolan, Stephen K., Fernanda dos Reis, Thaila, Pedro Bom, Vinicius Leite, Alves de Castro, Patricia, Hagiwara, Daisuke, Alowni, Raneem, Jones, Gary W., Doyle, Sean, Brown, Neil Andrew and Goldman, Gustavo H. (2015) Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus. G3 : Genes, Genomes, Genetics, 5. pp. 1525-1539. ISSN 2160-1836

O'Loughlin, Aran, McGee, Mark, Doyle, Sean and Earley, Bernadette (2014) Biomarker responses to weaning stress in beef calves. Research in Veterinary Science, 97 (2). pp. 457-463. ISSN 0034-5288

Johnson, Gemma, Ferrini, Arianna, Dolan, Stephen K., Nolan, Tania, Agrawal, Samir, Doyle, Sean and Bustin, Stephen A. (2014) Biomarkers for invasive aspergillosis: the challenges continue. Biomarkers in Medicine, 8 (3). pp. 429-451. ISSN 1752-0363

Owens, Rebecca A., Hammel, Stephen, Sheridan, Kevin J., Jones, Gary W. and Doyle, Sean (2014) A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus. PLoS ONE, 9 (9). e106942. ISSN 1932-6203

O’Keeffe, Grainne, Hammel, Stephen, Owens, Rebecca A., Keane, Thomas M., Fitzpatrick, David A., Jones, Gary W. and Doyle, Sean (2014) RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus. BMC Genomics, 15 (894). pp. 1-26. ISSN 1471-2164

Dolan, Stephen K., Owens, Rebecca A., O'Keefe, Grainne, Hammel, Stephen, Fitzpatrick, David A., Jones, Gary W. and Doyle, Sean (2014) Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus. Chemistry and Biology, 21 (8). pp. 999-2012. ISSN 1074-5521

Jones, Gary W., Doyle, Sean and Fitzpatrick, David A. (2014) The evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine. Gene, 549 (1). pp. 161-170. ISSN 0378-1119

Culleton, Bridget A., Lall, Patrick, Kinsella, Gemma K., Doyle, Sean, McCaffrey, John G., Fitzpatrick, David A. and Burnell, Ann (2014) A role for the Parkinson’s disease protein DJ-1 as a chaperone and antioxidant in the anhydrobiotic nematode Panagrolaimus superbus. Cell Stress & Chaperones, 20 (1). pp. 121-137. ISSN 1355-8145

O'Keeffe, Grainne, Jöchl, Christoph, Kavanagh, Kevin and Doyle, Sean (2013) Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bc deletion in Aspergillus fumigatus. Protein Science, 22 (11). pp. 1612-1622. ISSN 0961-8368

Collins, Cassandra, Keane, Thomas M., Turner, Daniel J., O'Keefe, Grainne, Fitzpatrick, David A. and Doyle, Sean (2013) Genomic and Proteomic Dissection of the Ubiquitous Plant Pathogen, Armillaria mellea: Toward a New Infection Model System. Journal of Proteome Research, 12. pp. 2552-2570. ISSN 1535-3893

Shinoy, Minu, Dennehy, Ruth, Coleman, Elaine, Carberry, Stephen, Schaffer, Kirsten, Callaghan, Maire, Doyle, Sean and McClean, Siobhan (2013) Immunoproteomic Analysis of Proteins Expressed by Two Related Pathogens, Burkholderia multivorans and Burkholderia cenocepacia, during Human Infection. PLoS ONE, 8 (11). ISSN 1932-6203

Keady, S.M., Kenny, D.A., Ohlendieck, Kay, Doyle, Sean, Keane, M.G. and Waters, S.M. (2013) Proteomic profiling of bovine M. longissimus lumborum from Crossbred Aberdeen Angus and Belgian Blue sired steers varying in genetic merit for carcass weight. Journal of Animal Science, 91 (2). pp. 654-665. ISSN 0021-8812

O’Loughlin, Aran, Lynn, David J., McGee, Mark, Doyle, Sean, McCabe, Matthew and Earley, Bernadette (2012) Transcriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology. BMC Genomics, 13 (250). pp. 1-18. ISSN 1471-2164

O'Hanlon, Karen, Gallagher, Lorna, Schrettl, Markus, Jöchl, Christoph, Kavanagh, Kevin, Larsen, Thomas O. and Doyle, Sean (2012) Nonribosomal Peptide Synthetase Genes pesL and pes1 Are Essential for Fumigaclavine C Production in Aspergillus fumigatus. Applied and Environmental Microbiology , 78 (10). pp. 3166-3176. ISSN 0099-2240

Marquesa, Marco P.C., Walshe, Kieran, Doyle, Sean, Fernandesa, Pedro and de Carvalhoa, Carla C.C.R. (2012) Anchoring high-throughput screening methods to scale-up bioproduction of siderophores. Process Biochemistry, 47 (3). pp. 416-421. ISSN 1359-5113

Lynch, Eilish M., McGee, Mark, Doyle, Sean and Earley, Bernadette (2012) Effect of pre-weaning concentrate supplementation on peripheral distribution of leukocytes, functional activity of neutrophils, acute phase protein and behavioural responses of abruptly weaned and housed beef calves. BMC Veterinary Research, 8 (1). ISSN 1746-6148

Carberry, Stephen, Molloy, Emer, Hammel, Stephen, O'Keefe, Grainne, Jones, Gary W., Kavanagh, Kevin and Doyle, Sean (2012) Gliotoxin effects on fungal growth: Mechanisms and exploitation. Fungal Genetics and Biology, 49 (4). pp. 302-312. ISSN 1087-1845

O'Hanlon, Karen, Margison, Geoffrey P., Hatch, Amy, Fitzpatrick, David A., Owens, Rebecca A., Doyle, Sean and Jones, Gary W. (2012) Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus. Nucleic Acids Research, 40 (16). pp. 7806-7820. ISSN 0305-1048

Gallagher, Lorna, Owens, Rebecca A., Dolan, Stephen K., O'Keefe, Grainne, Schrettl, Markus, Kavanagh, Kevin, Jones, Gary W. and Doyle, Sean (2012) The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis. Eukaryotic Cell, 11 (10). pp. 1226-1238. ISSN 1535-9778

Doyle, Sean (2011) The Detection of Parvoviruses. Methods in Molecular Biology, 665. pp. 213-231. ISSN 1064-3745

Lynch, E.M., McGee, M., Doyle, Sean and Earley, B. (2011) Effect of post-weaning management practices on physiological and immunological responses of weaned beef calves. Irish Journal of Agricultural and Food Research, 50 (2). pp. 161-174. ISSN 07916833

O'Loughlin, Aran, McGee, Mark, Waters, Sinead M., Doyle, Sean and Earley, Bernadette (2011) Examination of the bovine leukocyte environment using immunogenetic biomarkers to assess immunocompetence following exposure to weaning stress. BMC Veterinary Research, 7 (45). ISSN 1746-6148

Doyle, Sean (2011) Fungal proteomics: from identification to function. FEMS Microbiology Letters, 321 (1). pp. 1-9. ISSN 0378-1097

Doyle, Sean (2011) Fungal proteomics: from identitcation to function. Microbiology Letters, 321. pp. 1-9.

O'Shaughnessy, Luke, Carr, Michael, Crowley, Brendan, Carberry, Stephen and Doyle, Sean (2011) Recombinant expression and immunological characterisation of proteins derived from human metapneumovirus. Journal of Clinical Virology, 52 (3). pp. 236-243. ISSN 1386-6532

Davis, Carol, Gordon, Natasha, Murphy, Sinead, Singh, Ishwar , Kavanagh, Kevin, Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642

O'Hanlon, Karen, Cairns, Timothy, Stack, Deirdre, Schrettl, Markus, Bignell, Elaine, Kavanagh, Kevin, Miggin, Sinead, O'Keeffe, Grainne, Larsen, Thomas and Doyle, Sean (2011) Targeted Disruption of Nonribosomal Peptide Synthetase pes3 Augments the Virulence of Aspergillus fumigatus. Infection and Immunity, 79 (10). pp. 3978-3992. ISSN 0019-9567

Davis, Carol, Carberry, Stephen, Schrettl, Markus, Singh, Ishwar , Stephens, John C., Barry, Sarah M., Kavanagh, Kevin, Challis, Gregory L., Brougham, Dermot and Doyle, Sean (2011) The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus. Chemistry and Biology, 18. pp. 542-552. ISSN 1074-5521

Lynch, Eilish M., Earley, Bernadette, McGee, Mark and Doyle, Sean (2010) Characterisation of physiological and immunological responses in beef cows to abrupt weaning and subsequent housing. BMC Veterinary Research, 6 (37). pp. 1-8. ISSN 1746-6148

Lynch, E.M., Earley, B., McGee, M. and Doyle, Sean (2010) Effect of abrupt weaning at housing on leukocyte distribution, functional activity of neutrophils, and acute phase protein response of beef calves. BMC Veterinary Research, 6 (39). pp. 1-9. ISSN 1746-6148

Schrettl, Markus, Carberry, Stephen, Kavanagh, Kevin, Haas, Hubertus, Jones, Gary W., O'Brien, Jennifer, Nolan, Aine, Stephens, John C., Fenelon, Orla and Doyle, Sean (2010) Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin. PLOS Pathogens, 6 (6). ISSN 1553-7366

Gaffney, Mark, Doyle, Sean and Murphy, Richard (2009) Optimization of Xylanase Production by Thermomyces Ianuginosus in Solid State Fermentation. Bioscience, Biotechnology, and Biochemistry, 74 (12). pp. 2640-2644. ISSN 0916-8451

Gaffney, Mark, Carberry, Stephen, Doyle, Sean and Murphy, Richard (2009) Purification and characterisation of a xylanase from Thermomyces lanuginosus and its functional expression by Pichia pastoris. Enzyme and Microbial Technology, 45 (5). pp. 348-354. ISSN 0141-0229

Stack, Deirdre, Frizzell, Aisling, Tomkins, Karen and Doyle, Sean (2009) Solid Phase 4′-Phosphopantetheinylation: Fungal Thiolation Domains are Targets for Chemoenzymatic Modification. Bioconjugate Chemistry, 20 (8). pp. 1514-1522. ISSN 1043-1802

Stack, Deirdre, Neville, Claire and Doyle, Sean (2007) Nonribosomal peptide synthesis in Aspergillus fumigatus and other fungi. Microbiology, 153 (5). pp. 1297-1306. ISSN 1465-2080

Corcoran, A., Kerr, S., Elliott, G., Koppelman, M. and Doyle, Sean (2007) Improved detection of acute parvovirus B19 infection by immunoglobulin M EIA in combination with a novel antigen EIA. Vox Sanguinis, 96 (3). pp. 216-222. ISSN 0042-9007

Vickers, Imelda, Reeves, Emer P., Kavanagh, Kevin and Doyle, Sean (2007) Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus. Protein Expression and Purification, 53 (1). pp. 216-224. ISSN 1046-5928

Carberry, Stephen and Doyle, Sean (2007) Proteomic studies in biomedically and industrially relevant fungi. Cytotechnology, 53 (1-3). pp. 95-100. ISSN 0920-9069

Reeves, Emer P., Reiber, Kathrin, Neville, Claire, Scheibner, Olaf, Kavanagh, Kevin and Doyle, Sean (2006) A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus. The FEBS Journal, 273 (13). pp. 3038-3053. ISSN 1742-464X

Carberry, Stephen, Neville, Claire M., Kavanagh, Kevin and Doyle, Sean (2006) Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: Identification and characterisation of an elongation factor 1B protein with glutathione transferase activity. Biochemical and Biophysical Research Communications, 341 (4). pp. 1096-1104. ISSN 0006-291X

Corcoran, A., Crowley, B., Dewhurst, C., Pizer, B.L. and Doyle, Sean (2006) Establishment of Functional B Cell Memory Against Parvovirus B19 Capsid Proteins May be Associated With Resolution of Persistent Infection. Journal of Medical Virology, 78 (1). pp. 125-128. ISSN 0146-6615

Doyle, Sean and Corcoran, Amanda (2006) The Immune Response to Parvovirus B19 Exposure in previously Seronegative and Seropositive Individuals. Journal of Infectious Diseases, 194 (2). pp. 154-158. ISSN 0022-1899

Reiber, Kathrin, Reeves, Emer P., Neville, Claire M., Winkler, Robert, Gebhardt, Peter, Kavanagh, Kevin and Doyle, Sean (2005) The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron. FEMS Microbiology Letters, 248 (1). pp. 83-91. ISSN 0378-1097

Neville, Claire, Murphy, Alan, Kavanagh, Kevin and Doyle, Sean (2005) A 4'-Phosphopantetheinyl Transferase Mediates Non-Ribosomal Peptide Synthetase Activation in Aspergillus fumigatus. ChemBioChem, 6 (4). pp. 679-685.

Burns, Claire, Geraghty, Rachel, Neville, Claire, Murphy, Alan, Kavanagh, Kevin and Doyle, Sean (2005) Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus. Fungal Genetics and Biology, 42 (4). pp. 319-327. ISSN 1087-1845

Waters, Sinead M., Doyle, Sean, Murphy, Richard A. and Power, Ronan F.G. (2005) Development of solution phase hybridisation PCR-ELISA for the detection and quantification of Enterococcus faecalis and Pediococcus pentosaceus in Nurmi-type cultures. Journal of Microbiological Methods, 63 (3). pp. 264-275. ISSN 0167-7012

Corcoran, Amanda, Doyle, Sean, Allain, J.P., Candotti, D. and Parsyan, A. (2005) Letter to the Editor Evidence of Serological Cross-Reactivity between Genotype 1 and Genotype 3 Erythrovirus Infections. Journal of Virology, 79 (8). pp. 5238-5239.

Doyle, Sean and Corcoran, Amanda (2004) Advances in the biology, diagnosis and host-pathogen interactions of parvovirus B19. Journal of Medical Microbiology, 53. pp. 1-17.

Corcoran, Amanda, Mahon, Bernard P. and Doyle, Sean (2004) B Cell Memory Is Directed toward Conformational Epitopes of Parvovirus B19 Capsid Proteins and the Unique Region of VP1. Journal of Infectious Diseases, 189 (10). pp. 1873-1880. ISSN 0022-1899

Collins, Peter R., Stack, Colin M., O'Neill, Sandra M., Doyle, Sean, Ryan, Thecla, Brennan, Gerard, Mousley, Angela, Stewart, Michael, Maule, Aaron G., Dalton, John P. and Donnelly, Sheila (2004) Cathepsin L1, the Major Protease Involved in Liver Fluke (Fasciola hepatica) Virulence. Journal of Biological Chemistry, 279 (17). pp. 17038-17046. ISSN 0021-9258

Reeves, Emer P., Messina, C.G.M., Doyle, Sean and Kavanagh, Kevin (2004) Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella. Mycopathologia, 158 (1). pp. 73-79. ISSN 0301-486X

Doyle, Sean, Fox, M., Gray, G. and Kavanagh, Kevin (2004) Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development. Journal of Microbiological Methods, 56 (2). pp. 221-230. ISSN 0167-7012

McCarthy, Elaine, Stack, Colin, Donnelly, Sheila M., Doyle, Sean, Mann, Victoria H., Brindley, Paul J., Stewart, Michael, Day, Tim A., Maule, Aaron G. and Dalton, John P. (2004) Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum. International Journal of Parasitology, 34 (6). pp. 703-714. ISSN 0020-7519

O'Keeffe, Joseph, Doyle, Sean and Kavanagh, Kevin (2003) Exposure of the yeast Candida albicans to the anti-neoplastic agent adriamycin increases the tolerance to amphotericin B. Journal of Pharmacy and Pharmacology, 55 (12). pp. 1629-1633.

Mahon, Bernard P., Corcoran, Amanda, McParland, Peter, Davoren, Anne and Doyle, Sean (2003) Ex Vivo Cytokine responses against Parvovirus B19 Antigens in previously infected pregnant women. Journal of Medial Virology, 70 (3). pp. 475-480. ISSN 0146-6615

Dalton, John P., O'Neill, Sandra M., Stack, Colin M., Collins, Peter R., Walshe, Alan, Sekiya, Mary, Doyle, Sean, Mulcahy, Grace, Hoyle, Deborah, Khaznadji, Eric, Moire, Nathalie, Brennan, Gerard, Mousley, Angela, Kreshchenko, Natalia, Maule, Aaron G. and Donnelly, Sheila M. (2003) Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines. International Journal for Parasitology, 33 (11). pp. 1173-1181. ISSN 0020-7519

Deegan, Orla, Walshe, Kieran, Kavanagh, Kevin and Doyle, Sean (2003) Quantitative detection of C-reactive protein using phosphocholine-labelled enzyme or microspheres. Analytical Biochemistry, 312 (2). pp. 175-181. ISSN 0003-2697

Doyle, Sean and Daly, Paul (2003) The development of a competitive PCR-ELISA for the detection of equine herpesvirus-1. Journal of Virological Methods, 107 (2). pp. 237-244. ISSN 0166-0934

Doyle, Sean, Mahon, Bernard P., Corcoran, A. and Daly, P. (2002) High-Sensitivity PCR Detection of Parvovirus B19 Plasma. Journal of Clinical Microbiology, 40 (6). pp. 1958-1962.

Raab, Ulla, Beckenlehner, Karin, Lowin, Tosten, Niller, Hans-Helmut, Doyle, Sean and Modrow, Susanne (2002) NS1 Protein of Parvovirus B19 Interacts Directly with DNA Sequences of the p6 Promoter and with the Cellular Transcription Factors Sp1/Sp3. Virology, 293 (1). pp. 86-93. ISSN 0042-6822

Doyle, Sean, Daly, Paul and Collier, T. (2002) PCR-ELISA detection of Escherichia coli in milk. Letters in Applied Microbiology, 34 (3). pp. 222-226. ISSN 0266-8254

Mahon, Bernard P., Doyle, Sean, Kavanagh, Kevin, Corcoran, Amanda and Ennis, O. (2001) Baculovirus expression of parvovirus B19 (B19V) NS1: utility in confirming recent infection. Journal of Clinical Virology, 22 (1). pp. 55-60. ISSN 1386-6532

Doyle, Sean, Kerr, S., O'Keeffe, Grainne, O'Carroll, D., Daly, P. and Kilty, C. (2000) Detection of parvovirus B19 IgM by antibody capture enzyme immunoassay: receiver operating characteristic analysis. Journal of Virological Methods, 90 (2). pp. 143-1522. ISSN 0166-0934

Cotter, Gary, Doyle, Sean and Kavanagh, Kevin (2000) Development of an insect model for the in vivo pathogenicity testing of yeasts. FEMS Immunology and Medical Microbiology, 27 (2). pp. 163-169. ISSN 0928-8244

Corcoran, Amanda, Doyle, Sean, Waldron, David, Nicholson, Alfred and Mahon, Bernard P. (2000) Impaired Gamma Interferon Responses against Parvovirus B19 by Recently Infected Children. Journal of Virology, 74 (21). pp. 9903-9910. ISSN 0022-538X

Flendring, Leonard M., Chamuleau, Robert A.F.M., Maas, Martinus A.W., Daalhuisen, Joost, Hasset, Brian, Kilty, Cormac G., Doyle, Sean, Ladiges, Nita C.J.J., Jörning, George G.A., la Soe, John W., Sommeijer, Dirkje and te Velde, Anje A. (1999) Evaluation of a novel bioartificial liver in rats with complete liver ischemia: treatment efficacy and species-specific alpha-GST detection to monitor hepatocyte viability. Journal of Hepatology, 30 (2). pp. 311-321. ISSN 0168-8278

Kerr, S., O'Keeffe, Grainne, Kilty, C. and Doyle, Sean (1999) Undenatured parvovirus B19 antigens are essential for the accurate detection of parvovirus B19 IgG. Journal of Medical Virology, 57 (2). pp. 179-185. ISSN 0146-6615

Eckersall, P.D., Duthie, S., Safi, S., Moffatt, D., Horadagoda, N.U., Doyle, Sean, Parton, R., Bennett, D. and Fitzpatrick, J.L. (1999) An automated biochemical assay for haptoglobin: prevention of interference from albumin. Comparative Haematology International, 9 (3). pp. 117-124. ISSN 0938-7714

Kilty, Cormac, Doyle, Sean, Hassett, Brian and Manning, Fiona (1998) Glutathione S-transferases as biomarkers of organ damage: applications of rodent and canine GST enzyme immunoassays. Chemico-Biological Interactions, 111. pp. 123-135. ISSN 0009-2797

Clarke, H., Egan, DA, Heffernan, M., Doyle, Sean, Byrne, C., Kilty, C. and Ryan, MP (1997) α-glutathione s-transferase (α-GST) release, an early indicator of carbon tetrachloride hepatotoxicity in the rat. Human & Experimental Toxicology, 16 (3). pp. 154-157. ISSN 0960-3271

McCormack, Christine C., Hobson, Audrey H., Doyle, Sean, Jackson, John, Kilty, Cormac and Whitehead, Alexander S. (1996) Generation of soluble recombinant human acute phase serum amyloid A2 protein and its use in the development of an A-SAA specific ELISA. Journal of Immunological Methods, 198 (1). pp. 101-110. ISSN 0022-1759

Rees, Gareth W., Trull, Andrew K. and Doyle, Sean (1995) Evaluation of an Enzyme-Immunometric Assay for Serum α-Glutathione S-Transferase. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 32 (6). pp. 575-583. ISSN 1758-1001

Doyle, Sean, Schininà, M.E., Bossa, F. and Doonan, S. (1990) The amino acid sequence of cytosolic aspartate aminotransferase from human liver. Biochemical Journal, 270 (3). pp. 651-657. ISSN 0264-6021

Book Section

Corcoran, A. and Doyle, Sean (2006) Human Parvovirus B19: Molecular Virology, Clinical Features, Prevalence, Diagnosis and Control. In: Congenital and Other Related Infectious Diseases of the Newborn. Perspectives in Medical Virology (13). Elsevier, pp. 173-209. ISBN 9780444520746

Doyle, Sean (2001) Paravovirus B19 infection - an underestimated problem. In: The Irish Scientist. Samton Limited, p. 139. ISBN 1898706239